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tracking of stem cells by imaging modality

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This is very important assignment to me please do it carefully for me ((for the first question there will be( 5 parts) each part need short answer 3 to4 lines and for Question 2 the answer will be long need 500 words))
Stem cells, derived from bone marrow or umbilical cord, are increasingly used to treat disease. Regardless of stem cell origin, the challenge is that future clinical trials require that the location and number of such cells be tracked in vivo, over long periods of time. This is an emerging field and most of the work is still experimental and undertaken in animals. Please, use Web of Science or SCOPUS to find the relevant information
Q1: Investigate and report on the number of scientific publications that discuss brain imaging [consider all imaging modalities] for the tracking of stem cells in vivo. In your answer address the following points:
a. State the types of imaging modality used and how often they are reported in the context of stem cell tracking. How many research papers or reviews report on PET or SPECT??
b. Have any stem tracking studies using imaging been undertaken in humans??
c. What isotopes and tracers or ligands have been used??
d. Are there publications where more than one brain imaging modality has been discussed?
e. What are the 10 most frequently cited publications dealing with the subject matter of brain imaging and stem cell tracking in vivo?(use the web of science)
Q2: State in your own words (in 500 words) what is the greatest challenge in tracking stems cells in vivo?

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