Vitamin D Research Project
Order Description
DRUG STUDIED; VITAMIN D
Mpharm 2nd year Project
• The originating species for the drug and/or its related molecules
• The mechanism of its action
• Examples of how it may be formulated
• How it may be analysed or quantified
PY5010 Groupwork exercise
You need to form groups of 4 students to do this work.
Your task is to research a drug which either is or is related to a natural product. You need to study and then present the chemistry of your drug.
Areas which you may consider are:
• Details of its structure, physical form and characteristics
• The originating species for the drug and/or its related molecules
• How your drug, or related molecules, are biosynthesised
• The mechanism of its action
• Examples of how it may be formulated
• How it may be analysed or quantified
You should get your information from journal articles or from textbooks. Websites may be used if you cannot find information elsewhere, however they must be reputable
(e.g. a university, NHS, official body). Journal articles accessed online do not count as websites (but as articles).
You should aim to find 6-10 good references
Good places to start include:
The British Pharmacopoeia
Derwick, P.M., Medicinal Natural Products: A Biosynthetic Approach
Patrick, G.L., Introduction to Medicinal Chemistry
For journal articles use the Web of Knowledge database (wok.mimas.ac.uk)
Your group will need to present your findings in two ways:
• A report of up to six pages (excluding diagrams and references)
• A summary poster which is informative and eye-catching
Each member will also need to write a one page (maximum) reflective piece on how they contributed to each element of the work. There will also be a questionnaire for
you to rate the contribution of your colleagues.
Timeline:
(all dates are latest time to complete each exercise – earlier completion is encouraged)
12th Jan Decide group members and inform Dr Carrington via email
Any students not grouped or with incomplete groups at this time will be put into groups.
19th Jan Email Dr Carrington with group’s choice of drug. This will then be approved. You may need to change if too many groups
pick the same drug. Assistance will be given to any group having problems finding a suitable drug – email for help.
26th Jan Submit, via StudySpace, a 1-2 page outline of the information collected and an outline of the report.
Formative feedback on this will assist with putting together the more detailed final document
23rd Feb Final submission of all documents via StudySpace
Marking criteria:
Report:
50% relevant scientific content relating to the drug being discussed
20% a logical and coherent presentation of the information which makes sense to an independent reader
20% choice of suitable references; clear citation of references using Vancouver Style
10% quality and consistency of presentation including spelling and grammar
Poster:
40% scientific content
40% technical design – making use of the poster format to present the information in a suitable and eye-catching way
20% quality and consistency of presentation including spelling and grammar
(examples of scientific posters may be seen around the walls of the department in the main building)
This exercise contributes 30% of the module marks in the following proportion:
Report 15%, poster 10%; contribution to the task 5%
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